AUTHORS : Supha Nandhini Kannan, Venkateswaramurthy Nallasamy, Sambath Kumar Ramanathan DOI No. : DOI Link. : Antibiotic resistance is a global public health threat affecting both current and future generations and its misuse is a major driver of resistance. Worldwide extensive and over use of antibiotics has resulted in increase of resistance to them in bacteria. Hence, it results in reduced efficacy of antimicrobial drugs making the treatment of patients difficult, costly, or even impossible. In India, more than 700,000 people deaths occur due to antimicrobial resistance in the year of 2014. Resistance to antibiotics could lead to the deaths of ten million peoples a year globally by 2050. Antibiotic resistance particularly worrying in India, where hospital standards are inconsistent and antibiotics are readily available over the counter at pharmacies. Young adults in India had poor antibiotic knowledge and practice. Orientation programmes among the prescribers along with community awareness on rational use of antibiotics could reduce unnecessary use of antibiotics, thereby helping to minimize resistance development. Systemic efforts to collect data on epidemiology of antibiotic resistance have not yet been undertaken in India. This review focused on antibiotic resistance studies conducted in India from 2000-2016.