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Solanum indicum Linn.: An ethnopharmacological, phytochemical and pharmacological review

AUTHORS : Vinit Sharma, Kritika Hem, Ankit Seth, Santosh Kumar Maurya
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Background: Since ancient time human beings have been dependent on natural products for their primary healthcare requirements. Solanum indicum Linn. (Fam: Solanaceae) is an important plant in South East Asian countries not only for medicinal values but also for its economical importance. It is an erect under shrub available in Asia, Africa, Australia and India. Aim of the review: The purpose of this review is to exhibit up-to-date and comprehensive information about phytochemistry, pharmacological activities of the plant and has an insight into the opportunities for the future research and development of plant. Materials and methods: A bibliographic investigation was performed on all the available information regarding S. indicum via electronic search (using Pubmed, SciFinder, Scopus, Scirus, Google Scholar, JCCC@INSTIRC, Web of Science and a library search for articles published in peer-reviewed journals). Result: Various phytoconstituents from the plant has been reported, which includes phytoconstituents Steroidal saponins, steroidal glycoside, sesquiterpenoids, sesquiterpenoids, hydroxycoumarins, phenolic compounds, coumarins, coumarinolignoids alkaloids, saponin, fatty acid, glycerides of the oil, polysachharide, triterpenes. The plant was evaluated for a number of activities such as Antibacterial, Antioxidant, Anthelmintic, Antiplasmodial, Hepatoprotective, Anticancer, Laxative, Cardiotonic activity, CNS depressant and Anti hypertensive activity. Conclusion: Present review demonstrates that the S. indicum may serve as a good source of medicines in future. Majority of therapeutic claims for the plants in the various traditional medicines have been confirmed through experimental pharmacology. Key words: Solanum indicum, Antibacterial, Cardiotonic activity, Steroidal saponins

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